Here's the caveat: ditching regular software update install reminders is one thing, but not updating your Mac software is bad.
Freedom! (By the way, if you're also being plagued with constant 'Not Enough Storage' alerts on your iPhone, there's a fix for that, too.) Now, uncheck the box that says 'Automatically check for updates.' This does exactly what it sounds like: liberates you from the barrage of pop-up notifications we all hate.
First, go to System Preferences (either via the Apple icon on the navigation bar along the top of the screen or the cog wheel in the application dock).